GEO series
Proteolytic cleavage of Tie1 governs vascular response to inflammatory stimulations
GSE287671
Mus musculus
Expression profiling by high throughput sequencing
9 samples
2026/07/24
GPL21103
Summary
We here show that proteolytic cleavage of the Tie1 receptor evokes a vascular response to inflammatory stimulations such as TNFalpha and LPS. Resisting Tie1 cleavage reprogrammed EC gene networks, rendering them non-responsive to inflammatory stimulations.
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