Altered pathways in Cockayne syndrome: Involvement of MAPK, PI3K-Akt, extracellular matrix, inflammation, and neuronal signaling
RNA-seq (gene expression) · mouse · 30 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 30 samples: 6 conditions, mostly with about 5 replicates eachGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Altered pathways in Cockayne syndrome: Involvement of MAPK, PI3K-Akt, extracellular matrix, inflammation, and neuronal signalingDNA repair · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE288213_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1216576 and SRA study SRP560369. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 30 samples.
How we read this: 6 replicated groups read from 30 sample titles; they account for 30 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8761327 WT brain 1m15d 1_1 WT brain 1m15d 1
- GSM8761328 WT brain 1m15d 1_2 WT brain 1m15d 1
- GSM8761329 WT brain 1m15d 1_3 WT brain 1m15d 1
- GSM8761330 WT brain 1m15d 1_4 WT brain 1m15d 1
- GSM8761331 WT brain 1m15d 1_5 WT brain 1m15d 1
- GSM8761332 WT brain 12m 1_1 WT brain 12m 1
- GSM8761333 WT brain 12m 1_2 WT brain 12m 1
- GSM8761334 WT brain 12m 1_3 WT brain 12m 1
- GSM8761335 WT brain 12m 1_4 WT brain 12m 1
- GSM8761336 WT brain 12m 1_5 WT brain 12m 1
- GSM8761337 WT brain 24m 1_1 WT brain 24m 1
- GSM8761338 WT brain 24m 1_2 WT brain 24m 1
- GSM8761339 WT brain 24m 1_3 WT brain 24m 1
- GSM8761340 WT brain 24m 1_4 WT brain 24m 1
- GSM8761341 WT brain 24m 1_5 WT brain 24m 1
- GSM8761342 Csa brain 1m15d 1_1 Csa brain 1m15d 1
- GSM8761343 Csa brain 1m15d 1_2 Csa brain 1m15d 1
- GSM8761344 Csa brain 1m15d 1_3 Csa brain 1m15d 1
- GSM8761345 Csa brain 1m15d 1_4 Csa brain 1m15d 1
- GSM8761346 Csa brain 1m15d 1_5 Csa brain 1m15d 1
- GSM8761347 Csa brain 12m 1_1 Csa brain 12m 1
- GSM8761348 Csa brain 12m 1_2 Csa brain 12m 1
- GSM8761349 Csa brain 12m 1_3 Csa brain 12m 1
- GSM8761350 Csa brain 12m 1_4 Csa brain 12m 1
- GSM8761351 Csa brain 12m 1_5 Csa brain 12m 1
- GSM8761352 Csa brain 24m 1_1 Csa brain 24m 1
- GSM8761353 Csa brain 24m 1_2 Csa brain 24m 1
- GSM8761354 Csa brain 24m 1_3 Csa brain 24m 1
- GSM8761355 Csa brain 24m 1_4 Csa brain 24m 1
- GSM8761356 Csa brain 24m 1_5 Csa brain 24m 1
- GSE272272 Changes in the astrocyte translatome induced by developmental ethanol mediate dysregulation of neuronal development: role of the extracellular matrix and relevance to Fetal Alcohol Spectrum Disorders 48 samples shares extracellular, neuronal, matrix
- GSE295428 Spaceflight induces systemic effects on extracellular matrix and immune system in different age-stages 229 samples shares extracellular, matrix
- GSE287100 Sex-specific extracellular matrix remodeling in skeletal muscle after extended immobilization 112 samples shares extracellular, matrix
- GSE293374 An extracellular matrix niche secreted by epithelial cells drives intestinal organoid formation (RNA-seq) 44 samples shares extracellular, matrix
- GSE264169 Modulating the Extracellular Matrix to Treat Wound Healing Defects in Ehlers-Danlos Syndrome 35 samples shares extracellular, matrix
- GSE289885 Hybrid hydrogel–extracellular matrix scaffolds identify biochemical and mechanical signatures of cardiac ageing 29 samples shares extracellular, matrix
- GSE269446 In vivo CRISPR screens in Head and Neck Cancer reveal that Uchl5 modulates extracellular matrix deposition to promote immune evasion 23 samples shares extracellular, matrix
- GSE249085 TSG-6 mediated extracellular matrix modifications regulate hypoxic-ischemic brain injury 20 samples shares extracellular, matrix
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.