High levels of endogenous Omega-3 Fatty Acids prolong the lifespan, promote antigen presentation, and improve DC-based cancer vaccine efficacy in mice
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples: 6 conditions, mostly in triplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- High Levels of Endogenous Omega-3 Fatty Acids Promote Dendritic Cell Antigen Presentation and Improve Dendritic Cell-Based Cancer Vaccine Efficacy in MiceCancer immunology research · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE288336_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1216960 and SRA study SRP560591. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 18 samples.
How we read this: 6 replicated groups read from 18 sample titles; they account for 18 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8765546 WT_D0_rep1 WT_D0
- GSM8765547 WT_D0_rep2 WT_D0
- GSM8765548 WT_D0_rep3 WT_D0
- GSM8765549 FAT1_D0_rep1 FAT1_D0
- GSM8765550 FAT1_D0_rep2 FAT1_D0
- GSM8765551 FAT1_D0_rep3 FAT1_D0
- GSM8765552 WT_NT_rep1 WT_NT
- GSM8765553 WT_NT_rep2 WT_NT
- GSM8765554 WT_NT_rep3 WT_NT
- GSM8765555 FAT1_NT_rep1 FAT1_NT
- GSM8765556 FAT1_NT_rep2 FAT1_NT
- GSM8765557 FAT1_NT_rep3 FAT1_NT
- GSM8765558 WT_LPSgp100_rep1 WT_LPSgp100
- GSM8765559 WT_LPSgp100_rep2 WT_LPSgp100
- GSM8765560 WT_LPSgp100_rep3 WT_LPSgp100
- GSM8765561 FAT1_LPSgp100_rep1 FAT1_LPSgp100
- GSM8765562 FAT1_LPSgp100_rep2 FAT1_LPSgp100
- GSM8765563 FAT1_LPSgp100_rep3 FAT1_LPSgp100
- GSE277705 Integrated stress response inhibition prolongs the lifespan of a Pelizaeus-Merzbacher disease mouse model by increasing oligodendrocyte survival. 57 samples shares lifespan, prolong
- GSE281695 Local radiation enhances systemic CAR T-cell efficacy by augmenting antigen crosspresentation and T-cell infiltration 25 samples shares presentation, efficacy
- GSE63804 Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo 22 samples shares endogenous, promote
- GSE291440 GA-Camk2a mouse RNAseq data for the manuscript by Rezaei et al: Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mouse model 21 samples shares lifespan, prolong
- GSE262778 Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mouse model 15 samples shares lifespan, prolong
- GSE289729 GA-CFP data for the manuscript "Correction of dysregulated lipid metabolism normalizes gene expression in oligodendrocytes and prolongs lifespan in female poly-GA C9orf72 mouse model" 13 samples shares lifespan, prolong
- GSE227998 TET2 Promotes Tumor Antigen Presentation and T Cell-Directed Tumor Cell Cytotoxicity Which is Enhanced by Vitamin C Treatment 12 samples shares presentation, promote
- GSE277294 Dietary fiber promotes antigen presentation on intestinal epithelial cells and development of small intestinal CD4+CD8αα+ intraepithelial T cells 11 samples shares presentation, promote
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.