GEO series
The Retinal Determination Gene Network can confer chemoresistant properties to AML [THP1_chip_rna]
GSE288498
Homo sapiens
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
23 samples
2025/12/03
GPL34284
Summary
SIX1 is a target of MLL-AF9 and MOZ-TIF2 fusions in murine models of AML. SIX1 is also expressed in a subset of human AML cell lines. Being a transcription factor we have studied the functional loss of SIX1 in this cell line.
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