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Single-Cell RNA Sequencing of Bone Marrow ILC2p and CHILPs, and Lung and Mesenteric Lymph Node ILC2s

GSE288743 Mus musculus Expression profiling by high throughput sequencing 9 samples Submitted 2025/06/12 Platform GPL30172
Summary
To explore potential tissue origins of iILC2 during helminth infection, we performed single-cell RNA sequencing (scRNA-seq) of ILC2 and ILC progenitors using the 10x Genomics platform. Intestine draining mesenteric lymph nodes (Mes LN), lung, and bone marrow (BM) were collected 5 days post infection (dpi) with Nippostrongylus brasiliensis.
Published in
Rapid group-2 innate lymphoid cell mobilization from the intestine aids in early lung defense and repair
Can UI, Stenske SE, Rosenbaum MD et al. · Cell reports 2025 · PMID 40543040 · doi:10.1016/j.celrep.2025.115868
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Also filed as BioProject PRJNA1219175 and SRA study SRP561531. Searching any of these in the dataset finder brings you back here.

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