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Transcriptome profiling of urothelial cells after exposure to low-grade oxidative stress

GSE288905 Homo sapiens Expression profiling by high throughput sequencing 8 samples Submitted 2025/03/26 Platform GPL24676
Summary
In this study, we aimed to determine the overall effect of glucose oxidase (GO) on transcriptomic profile of urothelial cells using RNA sequencing. Our study represents a reference database that could lead to a better understanding of the link between oxidative stress and innate immune response of urothelial cells leading to continuous cycle of inflammation in IC/BPS pathology. Furthermore, the study sets grounds for future studies exploring potential biomarkers and therapeutic targets for IC/PBS diagnosis and treatment.
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Direct links to NCBI, no account and no request form: the whole study as GSE288905_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 8 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1220002 and SRA study SRP561966. Searching any of these in the dataset finder brings you back here.

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