Human CD14+ monocytes from volunteers before and after a 3 hours, 24 hours and 120 hours-period of methotrexate intake. METOMAC trial
RNA-seq (gene expression) · human · 20 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Monocytes from inflammatory arthritis patients accumulate methotrexate and their transcriptome predicts methotrexate clinical responseCellular and molecular life sciences : CMLS · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE289101_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1221539 and SRA study SRP562706. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 20 more — browse all 20 samples with per-sample file links →
- GSE279719 Human CD14+ monocytes from early inflammatory arthritis patients before and after a 5day-and 30day-period of methotrexate treatment 72 samples shares cd14, methotrexate, monocytes
- GSE60601 Gene expression data from CD14++ CD16- classical monocytes from healthy volunteers and patients with pancreatic ductal adenocarcinoma 12 samples shares cd14, volunteers, monocytes
- GSE186500 RNAseq analysis of human CD14+ monocytes exposed or not to IL4 and ligands of Aryl Hydrocarbon Receptor 42 samples shares cd14, monocytes
- GSE294225 Transcriptional profiles are dramatically altered in circulating CD14+ monocytes in Rheumatoid Arthritis [RNA-seq] 24 samples shares cd14, monocytes
- GSE214091 RNAseq analysis of human CD14+ monocytes exposed to an agonist of Aryl Hydrocarbon Receptor 18 samples shares cd14, monocytes
- GSE217459 Gene expression of CD14+ peripheral blood monocytes in different phases of chronic HBV infection 7 samples shares cd14, monocytes
- GSE253495 Human CD14+ monocytes from rheumatoid arthritis patients before and after a 3-month period of Upadacitinib treatment 6 samples shares cd14, monocytes
- GSE256291 Comparing transcriptional profiles of CD14+ monocytes from melanoma patients and healthy donors by scRNA-seq. 4 samples shares cd14, monocytes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.