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Mapping CMV-Related Immune Signatures in Blood, Aorta, and Adipose Tissue

GSE289253 Homo sapiens Expression profiling by high throughput sequencing 7 samples Submitted 2025/11/01 Platform GPL24676
Summary
Cytomegalovirus (CMV) is a chronic herpes virus infection humans have co-evolved with. CMV infects immune and non-immune cells and alters the immune cell repertoire. CMV seropositivity has been associated with diseases of aging, including cardiovascular diseases. This study aims to deeply phenotype immune cell changes in blood, large arterial blood vessels, and perivascular adipose tissue to understand the role of CMV in cardiovascular disease.
Published in
Mapping CMV-related immune signatures in blood, aorta and perivascular mediastinal adipose tissue
Labeb C, Obare LM, Sheng Q et al. · Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2025 · PMID 41194668 · doi:10.1098/rstb.2024.0401
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Direct links to NCBI, no account and no request form: the whole study as GSE289253_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 7 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1222089 and SRA study SRP563096. Searching any of these in the dataset finder brings you back here.

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