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Natural killer cells’ functional impairment drives the immune escape of pre-malignant clones in early-stage myelodysplastic syndromes

GSE289476 Homo sapiens Genome binding/occupancy profiling by high throughput sequencing 16 samples 2025/03/05 GPL24676
Summary
Early therapeutic interventions following cancer detection are known to extend patient survival. A key challenge is dissecting preneoplastic disease states' biological mechanisms that precede tumorigenesis to slow down disease progression and/or mitigate disease-related comorbidities.
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