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SOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1

GSE290170 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/06/30 Platform GPL16791
Summary
The goals of this study are to compare the differentially expressed genes between OE-NC and OE-SOX3 KGN cell lines based on RNA-seq data and some of these genes were validated by qRT–PCR. Further, the differentially expressed genes were devided into up-regulated and down-regulated genes for GO, GSEA and KEGG analysis.
Published in
SOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1
Cai R, Li C, Shi W et al. · Cellular and molecular life sciences : CMLS 2025 · PMID 40586822 · doi:10.1007/s00018-025-05797-4
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Also filed as BioProject PRJNA1226516 and SRA study SRP565463. Searching any of these in the dataset finder brings you back here.

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