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Transcriptomic Validation of ALS-Derived Motor Neurons Following m6A Hypomethylation Restoration

GSE290244 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2025/04/30 Platform GPL18573
Summary
In this experiment, we investigated transcriptomic alterations in iPSC-derived motor neurons from ALS patients following the restoration of m6A hypomethylation to mitigate neurodegenerative processes.
Published in
The motor neuron m6A repertoire governs neuronal homeostasis and FTO inhibition mitigates ALS symptom manifestation
Yen YP, Lung TH, Liau ES et al. · Nature communications 2025 · PMID 40307231 · doi:10.1038/s41467-025-59117-2
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Also filed as BioProject PRJNA1226637 and SRA study SRP565551. Searching any of these in the dataset finder brings you back here.

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