BMAL1-HIF2α heterodimers contribute to ccRCC [RNA-seq]
RNA-seq (gene expression) · human · 17 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 17 samples: 5 × Xenograft harvested from mice treated with vehicle control at ZT0 vs 5 × Xenograft harvested from mice treated with PT2399 at ZT0 vs 4 × Xenograft harvested from mice treated with vehicle control at ZT12 vs 3 × Xenograft harvested from mice treated with PT2399 at ZT12Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- BMAL1 and ARNT enable circadian HIF2α responses in clear cell renal cell carcinomaNature communications · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE290779_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1230097 and SRA study SRP567049. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 17 samples.
How we read this: 4 replicated groups read from 17 sample titles; they account for 17 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8821487 Xenograft harvested from mice treated with vehicle control at ZT0 1 Xenograft harvested fro…
- GSM8821488 Xenograft harvested from mice treated with vehicle control at ZT0 2 Xenograft harvested fro…
- GSM8821489 Xenograft harvested from mice treated with vehicle control at ZT0 3 Xenograft harvested fro…
- GSM8821490 Xenograft harvested from mice treated with vehicle control at ZT0 4 Xenograft harvested fro…
- GSM8821491 Xenograft harvested from mice treated with vehicle control at ZT0 5 Xenograft harvested fro…
- GSM8821492 Xenograft harvested from mice treated with PT2399 at ZT0 1 Xenograft harvested fro…
- GSM8821493 Xenograft harvested from mice treated with PT2399 at ZT0 2 Xenograft harvested fro…
- GSM8821494 Xenograft harvested from mice treated with PT2399 at ZT0 3 Xenograft harvested fro…
- GSM8821495 Xenograft harvested from mice treated with PT2399 at ZT0 4 Xenograft harvested fro…
- GSM8821496 Xenograft harvested from mice treated with PT2399 at ZT0 5 Xenograft harvested fro…
- GSM8821497 Xenograft harvested from mice treated with vehicle control at ZT12 1 Xenograft harvested fro…
- GSM8821498 Xenograft harvested from mice treated with vehicle control at ZT12 2 Xenograft harvested fro…
- GSM8821499 Xenograft harvested from mice treated with vehicle control at ZT12 3 Xenograft harvested fro…
- GSM8821500 Xenograft harvested from mice treated with vehicle control at ZT12 4 Xenograft harvested fro…
- GSM8821501 Xenograft harvested from mice treated with PT2399 at ZT12 1 Xenograft harvested fro…
- GSM8821502 Xenograft harvested from mice treated with PT2399 at ZT12 2 Xenograft harvested fro…
- GSM8821503 Xenograft harvested from mice treated with PT2399 at ZT12 3 Xenograft harvested fro…
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.