Methylation pseudotime analysis for label-free profiling of the temporal chromatin landscape with long-read and single-molecule resolution
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 62 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 62 samples: 62 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE291013_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1231388 and SRA study SRP689189. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 62 sample titles: 62 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8826682 Run01_Repli-ATAC_0h_IP
- GSM8826683 Run01_Repli-ATAC_1h_IP
- GSM8826684 Run01_Repli-ATAC_4h_IP
- GSM8826685 Run01_Repli-ATAC_16h_IP
- GSM8826686 Run01_Repli-ATAC_0h_noIP
- GSM8826687 Run01_Repli-ATAC_1h_noIP
- GSM8826688 Run01_Repli-ATAC_4h_noIP
- GSM8826689 Run01_Repli-ATAC_16h_noIP
- GSM8826690 Run02_Repli-ATAC_0h_IP
- GSM8826691 Run02_Repli-ATAC_1h_IP
- GSM8826692 Run02_Repli-ATAC_4h_IP
- GSM8826693 Run02_Repli-ATAC_16h_IP
- GSM8826694 Run02_Repli-ATAC_0h_noIP
- GSM8826695 Run02_Repli-ATAC_1h_noIP
- GSM8826696 Run02_Repli-ATAC_4h_noIP
- GSM8826697 Run02_Repli-ATAC_16h_noIP
- GSM8826779 BrdU 10m pulse 0h chase
- GSM8826780 BrdU 10m pulse 16h chase
- GSM8826781 BrdU 20m pulse 0h chase
- GSM8826782 BrdU 20m pulse 16h chase
- GSM8826783 BrdU 30m pulse 0h chase
- GSM8826784 BrdU 30m pulse 16h chase
- GSM8826785 BrdU 1h pulse 0h chase
- GSM8826786 BrdU 1h pulse 16h chase
- GSM8826787 Mock 0h
- GSM8826788 Mock 16h
- GSM8826789 BioRep1, BrdU 500 uM 0h
- GSM8826790 BioRep1, BrdU 500 uM 16h
- GSM8826791 BioRep1, Mock 500uM 0h
- GSM8826792 BioRep2, BrdU 500 uM 0h
- GSM8826793 BioRep2, BrdU 500 uM 16h
- GSM8826794 HUES64_Unlabeled
- GSM9644138 H9, BrdU 50uM, 10m pulse 0h chase
- GSM9644139 H9, BrdU 50uM, 10m pulse 16h chase
- GSM9644140 H9, BrdU 50uM, 30m pulse 0h chase
- GSM9644141 H9, BrdU 50uM, 1h pulse 0h chase
- GSM9644142 H9, Mock 0h
- GSM9644143 H9, Mock 16h
- GSM9644144 HUES8 TKO, BrdU 500 uM, 0h chase
- GSM9644145 HUES8 TKO, BrdU 500 uM, 16h chase
+ 22 more — browse all 62 samples with per-sample file links →
- GSE261788 AMAR-seq: automated multimodal sequencing of DNA methylation, chromatin accessibility, and RNA expression with single-cell resolution 83 samples shares methylation, resolution, chromatin
- GSE278068 Nanobody-tethered transposition for dual profiling of chromatin accessibility and DNA methylation 201 samples shares methylation, chromatin
- GSE54365 High-resolution mapping reveals a conserved, widespread, dynamic meiotically regulated mRNA methylation program 76 samples shares methylation, resolution
- GSE253736 Motif distribution and DNA methylation underlie distinct Cdx2 binding during development and homeostasis 43 samples shares methylation
- GSE169102 DNA methyltransferase 1 modulates mitochondrial function through bridging m5C RNA methylation 187 samples shares methylation
- GSE274367 H3K36 Methylation - a Guardian of Epigenome Integrity 164 samples shares methylation
- GSE289193 Histone H4 lysine 20 tri-methylation safeguards breast cancer lineage fidelity and unfolded protein response 160 samples shares methylation
- GSE272618 Single-Molecule Barcoding Technology for Single-Cell Genomics 140 samples shares single-molecule
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.