DNA methyltransferase 1 modulates mitochondrial function through bridging m5C RNA methylation
DNA methylation · mouse · 187 samples
- What it is
- DNA methylationChemical marks on DNA that help switch genes on or off.
- Organism
- Mus musculus (mouse)
- Samples
- 187 samples: 163 distinct titles, 13 of them repeatedGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- DNA methyltransferase 1 modulates mitochondrial function through bridging m(5)C RNA methylationMolecular cell · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE169102_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for beta-value tables or raw IDAT files among the supplementary files.
Also filed as BioProject PRJNA715210 and SRA study SRP311081. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 8 samples read as cases, 37 as controls.
How we read this: Read from 187 sample titles: 163 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM5176321 WT cortex 5 prime
- GSM5176322 Het cortex 5 prime
- GSM5176323 Hom cortex 5 prime
- GSM5176324 WT retina 3 prime
- GSM5176325 Het retina 3 prime
- GSM5176326 Hom retina 3 prime
- GSM5176327 WT retina 5 prime
- GSM5176328 Hom retina 5 prime
- GSM5176377 wt_cortex1_meth
- GSM5176378 wt_cortex_w1_meth
- GSM5176379 wt_cor_g5_meth
- GSM5176380 wt_cor_b6_meth
- GSM5176381 hom_cor_w4_meth
- GSM5176382 hom_cor_g1_meth
- GSM5176383 hom_cortex1_meth
- GSM5176384 het_cor_w3_meth
- GSM5176385 het_cortexG3_meth
- GSM5176386 het_cortexG4_meth
- GSM5176387 het_cortexG2_meth
- GSM5176388 het_cortex1_meth
- GSM5176389 het_cortex_w2_meth
- GSM5176390 mouse CB-8565
- GSM5176391 mouse CB-8566
- GSM5176392 mouse CB-8568
- GSM5176393 mouse CB-4719
- GSM5176394 mouse CB-4721
- GSM5176395 mouse CB-4722
- GSM5176396 mouse CB-4723
- GSM5176397 Neuron J1-9
- GSM5176398 Neuron 29-9
- GSM5176399 Neuron J1-12
- GSM5176400 Neuron 29-12
- GSM5176401 mouse CB-0076
- GSM5176402 mouse CB-0077
- GSM5176403 mouse CB-0082
- GSM5176404 mouse CB-0086
- GSM5176405 mouse CB-0087
- GSM5176406 mouse CB-0088
- GSM5176407 mESC-J1-1
- GSM5176408 mESC-HOM-1
+ 147 more — browse all 187 samples with per-sample file links →
- GSE261788 AMAR-seq: automated multimodal sequencing of DNA methylation, chromatin accessibility, and RNA expression with single-cell resolution 83 samples shares methylation
- GSE278068 Nanobody-tethered transposition for dual profiling of chromatin accessibility and DNA methylation 201 samples shares methylation
- GSE277025 Inhaled Xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy 192 samples shares modulates
- GSE274367 H3K36 Methylation - a Guardian of Epigenome Integrity 164 samples shares methylation
- GSE289193 Histone H4 lysine 20 tri-methylation safeguards breast cancer lineage fidelity and unfolded protein response 160 samples shares methylation
- GSE71403 Tumor hypoxia causes DNA hypermethylation by reducing TET activity 99 samples shares methylation
- GSE54365 High-resolution mapping reveals a conserved, widespread, dynamic meiotically regulated mRNA methylation program 76 samples shares methylation
- GSE291013 Methylation pseudotime analysis for label-free profiling of the temporal chromatin landscape with long-read and single-molecule resolution 62 samples shares methylation
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.