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Gene expression profile at single cell level of intestinal epithelial cells from the distal colon

GSE291176 Mus musculus Expression profiling by high throughput sequencing 4 samples Submitted 2026/03/06 Platform GPL34290
Summary
In our inital data, we found AOM-treated AND-1 mutant mice (T819A ) showed increased colorectal cancer (CRC) incidence. Since common fragile sites (CFSs) instability were identified to be associated with CRC. We used colon as a model to perform single cell RNA sequencing to broadly characterize CFSs stability and CFSs-associate gene expression across cell types.
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Direct links to NCBI, no account and no request form: the whole study as GSE291176_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1232148 and SRA study SRP568164. Searching any of these in the dataset finder brings you back here.

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