YAP Induces a Pro-Renewal Metabolic State in Cardiomyocytes: Cardiomyocyte-enriched Datasets
RNA-seq (gene expression) · mouse · 14 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 14 samples: 5 × Control vs 4 × MEF2A vs 3 × YAP5SA vs 2 × YAP5SA_MEF2AGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- YAP Induces a Prorenewal Metabolic State in CardiomyocytesCirculation · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE291780_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1235232 and SRA study SRP569911. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 14 samples.
How we read this: 4 replicated groups read from 14 sample titles; they account for 14 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8842336 Control_1 Control
- GSM8842337 Control_2 Control
- GSM8842338 Control_3 Control
- GSM8842339 Control_4 Control
- GSM8842340 Control_5 Control
- GSM8842341 MEF2A_1 MEF2A
- GSM8842342 MEF2A_2 MEF2A
- GSM8842343 MEF2A_3 MEF2A
- GSM8842344 MEF2A_4 MEF2A
- GSM8842345 YAP5SA_1 YAP5SA
- GSM8842346 YAP5SA_2 YAP5SA
- GSM8842347 YAP5SA_3 YAP5SA
- GSM8842348 YAP5SA_MEF2A_1 YAP5SA_MEF2A
- GSM8842349 YAP5SA_MEF2A_2 YAP5SA_MEF2A
- GSE318612 Single-cell RNA sequencing of E18.5 mouse hindstomach epithelium and bulk RNA sequencing of its derived 3D organoids across distinct YAP activity states 19 samples shares yap, state
- GSE318022 Single-cell RNA sequencing of E18.5 mouse hindstomach epithelium and bulk RNA sequencing of its derived 3D organoids across distinct YAP activity states [scRNA-Seq] 3 samples shares yap, state
- GSE293469 Nanoplastics induces Arrhythmia in Human Stem-cells derived Cardiomyocytes [mouse hearts] 21 samples shares cardiomyocytes, induces
- GSE261940 Soluble ST2 induces cardiac contractile dysfunction by repressing mitochondrial electron transport chain genes in cardiomyocytes during fulminant myocarditis 20 samples shares cardiomyocytes, induces
- GSE294336 BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis [RNA-seq Aged_adult] 48 samples shares yap
- GSE294339 BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis [RNA-seq Col14] 48 samples shares yap
- GSE262620 Hepatic Yap1 activates systemic catabolism and muscle loss during organ repair: evidence for a common mechanism with cancer cachexia 36 samples shares yap
- GSE274982 PI3K regulates TAZ/YAP and mTORC1 and can synergistically be targeted in sarcomas 25 samples shares yap
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.