The RNA-binding E3 ligase MKRN2 selectively disrupts IL-6 translation to restrain inflammation [RNA-seq]
RNA-seq (gene expression) · mouse · 18 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 18 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE291859_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1235663 and SRA study SRP570214. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 18 more — browse all 18 samples with per-sample file links →
- GSE294583 Cold-inducible RNA-binding protein promotes lung fibroblast activation via TLR2/4-dependent IL-6 signaling: implications in pulmonary fibrosis 6 samples shares il-6, rna-binding
- GSE269772 SS18::SSX redistributes BAF chromatin remodelers selectively to activate and repress transcription [RNA-Seq] 46 samples shares selectively, rna-seq
- GSE286303 ZFP36-family RNA-binding proteins in regulatory T cells reinforce immune homeostasis [bulk RNA-seq - creERT2] 36 samples shares rna-binding, rna-seq
- GSE244619 ZFP36-family RNA-binding proteins in regulatory T cells reinforce immune homeostasis [bulk RNA-seq] 24 samples shares rna-binding, rna-seq
- GSE273092 Zfp697 is an RNA-binding protein that regulates skeletal muscle inflammation and remodeling (Zfp697 skeletal muscle knockout RNA-Seq of unloading-reloading protocol) 18 samples shares rna-binding, rna-seq
- GSE273647 Targeting nucleoporin 214 selectively eliminates leukemia stem cells by inducing ferroptosis [RNA-seq 3] 10 samples shares selectively, rna-seq
- GSE273648 Targeting nucleoporin 214 selectively eliminates leukemia stem cells by inducing ferroptosis [RNA-seq 4] 10 samples shares selectively, rna-seq
- GSE273642 Targeting nucleoporin 214 selectively eliminates leukemia stem cells by inducing ferroptosis [RNA-seq 1} 10 samples shares selectively, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.