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Multi-omics analysis of brain metastasis elucidates obesity induced prostaglandin crosstalk in tumor microenvironment restrain CD8T cell expansion (RNA-seq)

GSE291920 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2026/03/13 Platform GPL24676
Summary
Brain metastasis (BrM) is one of the most crucial complications in tumor patients. Obesity contributes to the metabolic remodeling of tumor cells, yet the how obesity impact tumor microenvironment still remains unclear. We utilized RNA-seq on 115 tumor or peritumor samples in 81 patients to investigate obesity's effect on BrM.
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Direct links to NCBI, no account and no request form: the whole study as GSE291920_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1235779. Searching any of these in the dataset finder brings you back here.

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