GEO series
Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast phase MPN through targetable overexpression of DYRK1A
GSE292030
Homo sapiens
Expression profiling by high throughput sequencing
10 samples
2025/03/27
GPL24676
Summary
To investigate the effect of chr21amp on cell differentiation, we performed droplet-based, high-throughput single-cell RNA-seq on Lin-CD34+ cells and total mononuclear cells.
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Paper (PMID 40490510) ↗
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