iPSC-derived NK cells engineered with CD226 effectively control acute myeloid leukemia
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Topic
- Acute myeloid leukemiaThis series is part of our curated briefing on it.
- Samples
- 12 samples: 3 × YT cells,OE226, vs 3 × YT cells,control, vs 3 × iNK cells,OE226, vs 3 × iNK cells,control,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- iPSC-derived NK cells engineered with CD226 effectively control acute myeloid leukemiaExperimental hematology & oncology · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE292274_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1237813 and SRA study SRP571332. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8855185 YT cells,OE226,1 YT cells,OE226,
- GSM8855186 YT cells,OE226,2 YT cells,OE226,
- GSM8855187 YT cells,OE226,3 YT cells,OE226,
- GSM8855188 YT cells,control,1 YT cells,control,
- GSM8855189 YT cells,control,2 YT cells,control,
- GSM8855190 YT cells,control,3 YT cells,control,
- GSM8855191 iNK cells,OE226,1 iNK cells,OE226,
- GSM8855192 iNK cells,OE226,2 iNK cells,OE226,
- GSM8855193 iNK cells,OE226,3 iNK cells,OE226,
- GSM8855194 iNK cells,control,1 iNK cells,control,
- GSM8855195 iNK cells,control,2 iNK cells,control,
- GSM8855196 iNK cells,control,3 iNK cells,control,
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.