← BioTransfer GEO Dataset Finder
GEO series

RNA-seq of ME-HESC in SRF-deficient vs Normal Conditions

GSE292411 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/09/30 Platform GPL24676
Summary
The transcription factor SRF plays known roles in mitogenic cell response and muscle cell development, and potential roles in endometrial stromal decidualization have been reported. After RNAi-based SRF knockdown in menstrual effluent-derived primary human endometrial stromal cells (ME-HESC), SRF-deficient cells exhibited disrupted cytoskeletal remodeling, cell cycle, and extracellular matrix genes. These data show that SRF is important for endometrial stromal cell homeostasis.
Published in
Serum response factor is essential for endometrial function and prevention of inflammatory fibrosis
Marquardt RM, Grimm SA, Wu SP et al. · Proceedings of the National Academy of Sciences of the United States of America 2025 · PMID 41150713 · doi:10.1073/pnas.2510060122
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE292411_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1238338 and SRA study SRP571663. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.