Clonal analysis and transcriptional profiling of ex vivo expanded mobilized peripheral blood hematopoietic stem and progenitor
RNA-seq (gene expression) · human · 17 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 17 samples: 5 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE292607_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1240289. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 10 samples.
How we read this: 5 replicated groups read from 17 sample titles; they account for 10 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8862348 CD34+ dp Transduced - patient 1 CD34+ dp Transduced - p…
- GSM8862349 CD34+ day4 Transduced - patient 1 CD34+ day4 Transduced -…
- GSM8862350 CD34+ day7 Transduced - patient 1 CD34+ day7 Transduced -…
- GSM8862351 CD34+ dp Transduced - patient 4 CD34+ dp Transduced - p…
- GSM8862352 CD34+ day4 Transduced - patient 4 CD34+ day4 Transduced -…
- GSM8862353 CD34+ day7 Transduced - patient 4 CD34+ day7 Transduced -…
- GSM8862354 TI24h_rep1 TI24h
- GSM8862355 TI72h_rep1 TI72h
- GSM8862356 TI24h_rep2 TI24h
- GSM8862357 TI72h_rep2 TI72h
- GSM8862366 CD34+ day4 Transduced
- GSM8862367 CD34+ day7 Transduced - A
- GSM8862368 CD34+ Untransduced
- GSM8862369 CD34+CD38- day7 Transduced
- GSM8862370 GMP-sorted day7 Transduced
- GSM8862371 F2F3-sorted day7 Transduced
- GSM8862372 CD34+ day7 Transduced - B
- GSE280113 Progenitor effects and unique transcriptomic signatures linked to differentiation phenotype in clonally expanded antigen-specific CD8 T memory stem cells (TSCM) 509 samples shares progenitor, expanded, clonal
- GSE208111 Transcriptome of human peripheral blood regulatory T cells with distinct ex vivo expansion profile 19 samples shares peripheral, blood, vivo
- GSE267423 In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles 11 samples shares hematopoietic, progenitor, vivo
- GSE267496 In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles [cell line panel] 11 samples shares hematopoietic, progenitor, vivo
- GSE281106 Single-cell RNA-seq of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases [scRNAseq_KR_SGI] 352 samples shares peripheral, blood
- GSE255685 Age-related transcriptomic differences in peripheral blood of adolescents with major depressive disorder 279 samples shares peripheral, blood
- GSE251778 Sex-specific and multiomic integration enhance accuracy of peripheral blood biomarkers of major depressive disorder [RNA-Seq] 169 samples shares peripheral, blood
- GSE327707 Sorted bulk RNA-seq profiling of human peripheral blood mononuclear cell populations across diverse in vitro immune stimuli 150 samples shares peripheral, blood
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.