Traumatic occlusion exacerbates bone resorption by modifying gene expression in the bone tissue of ligature-induced periodontitis in mice
RNA-seq (gene expression) · mouse · 32 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 32 samples: 32 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Traumatic Occlusion Exacerbates Bone Resorption by Modifying Gene Expression in the Bone Tissue of Ligature-Induced Periodontitis in MiceJournal of clinical periodontology · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE292710_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1241126 and SRA study SRP572612. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 32 sample titles: 32 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8863993 Co1B
- GSM8863994 Co1G
- GSM8863995 Co2B
- GSM8863996 Co2G
- GSM8863997 Co3B
- GSM8863998 Co3G
- GSM8863999 Co4B
- GSM8864000 Co4G
- GSM8864001 Tra1B
- GSM8864002 Tra1G
- GSM8864003 Tra2B
- GSM8864004 Tra2G
- GSM8864005 Tra3B
- GSM8864006 Tra3G
- GSM8864007 Tra4B
- GSM8864008 Tra4G
- GSM8864009 LiTra1B
- GSM8864010 LiTra1G
- GSM8864011 LiTra2B
- GSM8864012 LiTra2G
- GSM8864013 LiTra3B
- GSM8864014 LiTra3G
- GSM8864015 LiTra4B
- GSM8864016 LiTra4G
- GSM8864017 Li1B
- GSM8864018 Li1G
- GSM8864019 Li2B
- GSM8864020 Li2G
- GSM8864021 Li3B
- GSM8864022 Li3G
- GSM8864023 Li4B
- GSM8864024 Li4G
- GSE316444 Traumatic occlusion exacerbates bone resorption by modifying gene expression in the bone tissue of ligature-induced periodontitis in mice. 16 samples shares ligature-induced, periodontitis, exacerbates, resorption, traumatic, occlusion, modifying, bone
- GSE318778 Ligature-induced periodontitis in mice potentially accelerates CD4+ T cells senescence and exacerbates rheumatoid arthritis 12 samples shares ligature-induced, periodontitis, exacerbates
- GSE298066 Ligature-induced periodontitis (LIP) induces rapid alveolar bone loss followed by gingival immunosuppressive conditions 11 samples shares ligature-induced, periodontitis, bone
- GSE274253 An ageing bone marrow exacerbates lung fibrosis via a dysregulated regulatory T cell driven axis, fuelling profibrotic macrophage persistence. 44 samples shares exacerbates, bone
- GSE328134 Adipose tissue inflammation mediated by CCL19 overexpression exacerbates experimental periodontitis via elevated circulating saturated fatty acids and osteopontin in Western-diet-fed mice 36 samples shares periodontitis, exacerbates
- GSE327719 Estrogen deprivation alters gingival and dentoalveolar complex transcriptomes during ligature-induced periodontitis in mice 24 samples shares ligature-induced, periodontitis
- GSE339420 Polymicrobial-driven NLRP6 inflammasome regulates 1 IL-1b production and alveolar bone loss in a murine model of periodontitis 18 samples shares periodontitis, bone
- GSE274669 Modulation of Integrin α9β1 in Macrophages Reduces Periodontal Inflammation and Supports Alveolar Bone Preservation in Periodontitis [RNA-seq] 12 samples shares periodontitis, bone
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.