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Formyl peptide receptor 2 contributes to intestinal epithelium homeostasis by regulating intestinal stem cell proliferation and differentiation [scRNA-seq]

GSE292802 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/03/31 Platform GPL34290
Summary
To investigate the contribution of formyl peptide receptor 2 (FPR2) to intestinal epithelium homeostasis and the underlying mechanisms, we isolated small intestinal crypts from intestinal epithelial-specific knockout (Fpr2VKO) and control (Fpr2f/f) mice, isolated epithelial cells from the crypts and performed single-cell RNA sequencing (scRNA-Seq). The transcriptome profiles of Fpr2VKO and Fpr2f/f mice were compared.
Published in
Intestinal epithelial formyl peptide receptor 2 contributes to intestinal epithelium homeostasis and injury repair by regulating intestinal stem cell and transit-amplifying cell proliferation and differentiation
Yu S, Song L, Wunier et al. · Life metabolism 2026 · PMID 42099526 · doi:10.1093/lifemeta/loaf045
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Also filed as BioProject PRJNA1241283 and SRA study SRP572741. Searching any of these in the dataset finder brings you back here.

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