Open-Field Blast Injury Disrupts Corneal Gene Expression Linked to Ion Transport, Sensory Perception, and Neural Signaling
RNA-seq (gene expression) · mouse · 16 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 16 samples: 4 × BLAST-FS vs 4 × BLAST-MS vs 4 × Naive-FS vs 4 × Naive-MSGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Open-Field Blast Injury Disrupts Corneal Gene Expression Linked to Ion Transport, Sensory Perception, and Neural SignalingInvestigative ophthalmology & visual science · 2025
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE292886_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1241805 and SRA study SRP572997. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 4 replicated groups read from 16 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8868219 BLAST-FS1 BLAST-FS
- GSM8868220 BLAST-FS2 BLAST-FS
- GSM8868221 BLAST-FS3 BLAST-FS
- GSM8868222 BLAST-FS4 BLAST-FS
- GSM8868223 BLAST-MS1 BLAST-MS
- GSM8868224 BLAST-MS2 BLAST-MS
- GSM8868225 BLAST-MS3 BLAST-MS
- GSM8868226 BLAST-MS4 BLAST-MS
- GSM8868227 Naive-FS1 Naive-FS
- GSM8868228 Naive-FS2 Naive-FS
- GSM8868229 Naive-FS3 Naive-FS
- GSM8868230 Naive-FS4 Naive-FS
- GSM8868231 Naive-MS1 Naive-MS
- GSM8868232 Naive-MS2 Naive-MS
- GSM8868233 Naive-MS3 Naive-MS
- GSM8868234 Naive-MS4 Naive-MS
- GSE295750 RNA delivery to the corneal endothelium using charge-altering releasable transporters 16 samples shares transport, corneal
- GSE313803 HNRNPH2 variant linked to intellectual disability disrupts myelination by impairing oligodendrocyte differentiation 7 samples shares disrupts, linked
- GSE241542 A phosphate transporter in VIPergic neurons of the suprachiasmatic nucleus gates locomotor activity during the light/dark transition in mice 298 samples shares transport
- GSE266938 Deletion of SWI/SNF ATPase activity in hepatocytes of adult liver disrupts circadian gene expression and central liver functions [RNAseq] 82 samples shares disrupts
- GSE279388 Inactivation of Atp7b copper transporter in the intestinal epithelial cells is associated with altered lipid processing and cell growth machinery that are independent from hepatic copper accumulation and liver histology severity 76 samples shares transport
- GSE294558 Derepression of transposable elements in mouse prefrontal cortex disrupts social behavior 74 samples shares disrupts
- GSE228579 Chronic stress disrupts hepatic homeostasis and accelerates liver cancer progression through ADRB2 signaling 66 samples shares disrupts
- GSE262523 Diet-Induced Obesity Disrupts Sexually Dimorphic Gene Expression in Liver and Adipose Tissue in Mice 48 samples shares disrupts
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.