The effect of creatine supplementation on AOM/DSS induced colitis associated colorectal cancer in C57BL/6 mice
RNA-seq (gene expression) · mouse · 11 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 11 samples: 4 × C vs 4 × D vs 3 × NGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE293077_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1242752 and SRA study SRP573937. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 11 samples.
How we read this: 3 replicated groups read from 11 sample titles; they account for 11 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8875896 C2 C
- GSM8875897 C3 C
- GSM8875898 C4 C
- GSM8875899 C5 C
- GSM8875900 D2 D
- GSM8875901 D5 D
- GSM8875902 D6 D
- GSM8875903 D7 D
- GSM8875904 N2 N
- GSM8875905 N3 N
- GSM8875906 N4 N
- GSE295477 Wumei Wan Remodels the Tumor Immune Microenvironment via the IDO1-KYN-AHR Axis in AOM/DSS-Induced Colorectal Cancer Model. 15 samples shares aom, dss, colorectal, induced
- GSE271250 Dextran sulfate sodium (DSS)-induced colitis in WT and NAPRT KO mice [NAPRTKODSS] 24 samples shares dss, induced, colitis
- GSE331129 Transcriptome profiling of colorectal tissues from AOM-induced colorectal cancer mice with cigarette smoke exposure 18 samples shares aom, colorectal, induced
- GSE299286 Exploring the inhibitory mechanism of DSS-induced ulcerative colitis by Banxia Xiexin Decoctionthrough the combination of serumpharmacochemistry, networkpharmacology, and transcriptomics. 12 samples shares dss, induced, colitis
- GSE264408 Single-cell RNA sequencing of healthy mouse colon and mouse colon with acute or chronic colitis induced by DSS 10 samples shares dss, induced, colitis
- GSE262546 Paneth cell SIRT1 deficiency protects against DSS-induced colitis 10 samples shares dss, induced, colitis
- GSE281377 Microbiota exposure following DSS-induced colitis promotes Mincle-mediated training of myeloid progenitors 54 samples shares dss, induced, colitis
- GSE301604 TRMT6 mitigates susceptibility and progression of DSS-induced colitis multifacetedly via translational regulation 12 samples shares dss, induced, colitis
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.