TRMT6 mitigates susceptibility and progression of DSS-induced colitis multifacetedly via translational regulation
RNA-seq (gene expression) · mouse · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 12 samples: 6 × WT vs 6 × Trmt6 KOGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- TRMT6 mitigates susceptibility and progression of DSS-induced colitis multifacetedly via translational regulationScientific reports · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE301604_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1285701 and SRA study SRP598036. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 2 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9072218 WT rep1 WT
- GSM9072219 WT rep2 WT
- GSM9072220 WT rep3 WT
- GSM9072221 Trmt6 KO rep1 Trmt6 KO
- GSM9072222 Trmt6 KO rep2 Trmt6 KO
- GSM9072223 Trmt6 KO rep3 Trmt6 KO
- GSM9086290 WT rep1 WT
- GSM9086291 WT rep2 WT
- GSM9086292 WT rep3 WT
- GSM9086293 Trmt6 KO rep1 Trmt6 KO
- GSM9086294 Trmt6 KO rep2 Trmt6 KO
- GSM9086295 Trmt6 KO rep3 Trmt6 KO
- GSE281618 Cataloguing the postnatal small intestinal transcriptome during the period of susceptibility to necrotizing enterocolitis 48 samples shares susceptibility, colitis
- GSE265957 Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain 96 samples shares translational
- GSE314859 The degradation of maternal RNA-binding protein 4E-T regulates translational activation to ensure maternal-to-zygotic transition in mouse embryos 67 samples shares translational
- GSE327880 Neuronal activation triggers rapid biphasic FMRP-mediated translational control linking synaptic and nuclear regulation 51 samples shares translational
- GSE293841 Rps15 mutation drives B cell malignancy through translational rewiring, oxidative stress and genomic instability 51 samples shares translational
- GSE314176 Single cell and isoform-specific translational profiling of the mouse brain 25 samples shares translational
- GSE268058 PPARγ-dependent Remodeling of Translational Machinery in Adipose Progenitors is Impaired in Obesity 24 samples shares translational
- GSE247715 Cross-talks between metabolic and translational controls during beige adipocyte differentiation 18 samples shares translational
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.