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Effects of exercise and Phellodendron amurense extract in prostate cancer

GSE293221 Mus musculus Expression profiling by high throughput sequencing 9 samples Submitted 2025/04/07 Platform GPL21493
Summary
Oxidative stress, induced by chronic prostatic inflammation, impairs normal protective mechanisms in the prostate and increases the risk for cancer progression. The Phellodendron amurense extract (Nexrutine®) had similar effects as exercise in reducing highly aggressive tumors in the transgenic adenocarcinoma of the mouse prostate (TRAMP) model. In this study, we examined changes in the transcriptome to understand how these two interventions affect prostate cancer.
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Also filed as BioProject PRJNA1243357 and SRA study SRP573905. Searching any of these in the dataset finder brings you back here.

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