GEO series
Transcriptomic profiling of human trophoblast stem cells (hTSCs) and HTR-8/SVneo cells under normal and MYBL2 knockdown conditions
GSE293321
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2025/04/07
GPL16791
Summary
This dataset comprises the gene expression profiles of human trophoblast stem cells (hTSCs) and HTR-8/SVneo cells under WT and MYBL2 knockdown conditions. RNA sequencing (RNA-seq) was conducted to examine the effects of MYBL2 depletion on gene expression, with the goal of elucidating its role in trophoblast function, including stemness maintenance, differentiation, and invasion. This dataset offers valuable insights into the molecular mechanisms governed by MYBL2 in trophoblast biology and its potential relevance to pregnancy-related disorders.
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Paper (PMID 40294258) ↗
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