GEO series
Targeting WWP2 to restore mitochondrial OXPHOS integrity―a novel strategy to attenuate acute kidney injury to chronic kidney disease transition
GSE293589
Mus musculus
Expression profiling by high throughput sequencing
12 samples
2026/03/18
GPL23479
Summary
Analysis of kidney from transgenics depleted for renal tubular WW domain containing E3 ubiquitin protein ligase 2 (WWP2) then established a kidney unilateral ischemia reperfusion (UIR) injury in mice induce acute kidney injury (AKI) to chronic kidney disease (CKD) transition. Results provide insight into the role of WWP2 activation in AKI-to-CKD transition.
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Paper (PMID 41254942) ↗
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