GEO series
A next-generation inhaled aerosol COVID-19 vaccine boosts lung immunity in human
GSE294031
Homo sapiens
Expression profiling by high throughput sequencing
12 samples
2025/05/21
GPL30173
Summary
A new inhaled aerosol vaccine using chimpanzee adenoviral vectors induces robust mucosal immunity in the lungs, including T cell, innate, and antibody responses, providing broader protection against SARS-CoV-2 variants. This strategy is superior to intramuscular mRNA vaccines and prior SARS-CoV-2 infection.
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Paper (PMID 40603330) ↗
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