The effect of menin-inhibition on the human AML cell line MV4-11
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 22 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 22 samples: 11 × Vehicle vs 6 × SNDX vs 5 × MIGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed expression table (series matrix) and the array files, from NCBI.
- Paper
- Menin inhibition enhances graft-versus-leukemia effects by T-cell activation and endogenous retrovirus induction in AMLBlood · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294579_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1250521 and SRA study SRP578501. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 22 samples.
How we read this: 3 replicated groups read from 22 sample titles; they account for 22 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM7437956 Vehicle replicate 5 Vehicle
- GSM7437957 Vehicle replicate 4 Vehicle
- GSM7437958 Vehicle replicate 3 Vehicle
- GSM7437959 Vehicle replicate 2 Vehicle
- GSM7437960 Vehicle replicate 1 Vehicle
- GSM7437961 MI replicate 5 MI
- GSM7437962 MI replicate 4 MI
- GSM7437963 MI replicate 3 MI
- GSM7437964 MI replicate 2 MI
- GSM7437965 MI replicate 1 MI
- GSM8911719 Vehicle replicate 1 Vehicle
- GSM8911720 Vehicle replicate 2 Vehicle
- GSM8911721 Vehicle replicate 3 Vehicle
- GSM8911722 Vehicle replicate 4 Vehicle
- GSM8911723 Vehicle replicate 5 Vehicle
- GSM8911724 Vehicle replicate 6 Vehicle
- GSM8911725 SNDX replicate 1 SNDX
- GSM8911726 SNDX replicate 2 SNDX
- GSM8911727 SNDX replicate 3 SNDX
- GSM8911728 SNDX replicate 4 SNDX
- GSM8911729 SNDX replicate 5 SNDX
- GSM8911730 SNDX replicate 6 SNDX
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Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.