Transcriptomic Insights into the effect of Mesenchymal Stromal Cells Culture Medium on the Hematopoietic Stem/Progenitor Cells Co-culture
RNA-seq (gene expression) · human · 49 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 49 samples
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Differential effects of fetal bovine serum and human platelet lysate on mesenchymal stromal cell-mediated support of hematopoietic stem/progenitor cells: a functional and transcriptomic analysisStem cell research & therapy · 2025
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE294580_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1250525 and SRA study SRP578457. Searching any of these in the dataset finder brings you back here.
The sample list for this study is not cached yet. Press Load samples and it will be fetched from NCBI.
+ 49 more — browse all 49 samples with per-sample file links →
- GSE326276 Inhibition of inflammation and senescence with azole compound C7 enables expansion of hematopoietic stem and progenitor cells 45 samples shares hematopoietic, progenitor, stem
- GSE322893 Transcriptomic Analysis of Potency Associated Genes in Hematopoietic Stem and Progenitor Cells 27 samples shares hematopoietic, progenitor, stem
- GSE216842 Transcriptomic landscape of human primary stromal cells (fibroblasts, endothelial cells and mesenchymal stem cells) upon therapy-induced senescence (genotoxic chemotherapy） 24 samples shares mesenchymal, stromal, stem
- GSE267423 In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles 11 samples shares hematopoietic, progenitor, stem
- GSE318863 Ex vivo long-term expansion of human hematopoietic stem and progenitor cells as a tool for modeling vector integration sites and clonality 10 samples shares hematopoietic, progenitor, stem
- GSE263204 Single cell transcription profiles of hematopoietic stem and progenitor cells from Beta thalassemia transfusion dependent patients in steady state condition 10 samples shares hematopoietic, progenitor, stem
- GSE267496 In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles [cell line panel] 11 samples shares hematopoietic, progenitor, stem
- GSE280113 Progenitor effects and unique transcriptomic signatures linked to differentiation phenotype in clonally expanded antigen-specific CD8 T memory stem cells (TSCM) 509 samples shares progenitor, stem
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.