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Ultra-deep bulk RNA-seq from hESC-derived thyroid follicular cells

GSE295120 Homo sapiens Expression profiling by high throughput sequencing 9 samples Submitted 2025/08/13 Platform GPL18460
Summary
This study provides ultra-deep bulk RNA-seq data from human embryonic stem cell (hESC)-derived thyroid follicular cells. The NKX2-1GFP+ population was isolated using fluorescence-activated cell sorting (FACS) and subjected to RNA extraction. Library preparation was performed using the Ovation Solo RNA-seq System, followed by high-output sequencing on the Illumina HiSeq 1500 platform. Each sample generated approximately 400 million reads. These data enable transcriptomic analysis of differentiated thyroid lineage cells exposed to IFN-α and IFN-γ.
Published in
Transcriptomics of autoimmune diseases identifies FGFR1 as a target for pancreatic β-cell protection
Yi X, Zimath PL, Martin-Vazquez E et al. · Journal of autoimmunity 2025 · PMID 40782630 · doi:10.1016/j.jaut.2025.103469
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Direct links to NCBI, no account and no request form: the whole study as GSE295120_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 9 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1253580 and SRA study SRP580358. Searching any of these in the dataset finder brings you back here.

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