PRMT1 recruitment and H4R3Me2a modification in control and PRMT1-depleted trophoblast progenitor
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 25 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 25 samples: 25 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE295846_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1256477 and SRA study SRP581955. Searching any of these in the dataset finder brings you back here.
Any grouping that defines a comparison lives in the sample characteristics, which GEO records separately from the titles.
How we read this: Read from 25 sample titles: 25 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8958555 PRMT1 Control sample 1 (Cut & Run)
- GSM8958556 PRMT1 Control sample 2 (Cut & Run)
- GSM8958557 H4R3 Control sample 1 (Cut & Run)
- GSM8958558 H4R3 Control sample 2 (Cut & Run)
- GSM8958559 H4R3 Control sample 3 (Cut & Run)
- GSM8958560 RNAPol2 Control sample 1 (Cut & Run)
- GSM8958561 RNAPol2 Control sample 2 (Cut & Run)
- GSM8958562 IgG Control sample 1 (Cut & Run)
- GSM8958563 IgG Control sample 2 (Cut & Run)
- GSM8958564 PRMT1 knock down sample 1 (Cut & Run)
- GSM8958565 PRMT1 knock down sample 2 (Cut & Run)
- GSM8958566 PRMT1 knock down sample 3 (Cut & Run)
- GSM8958567 H4R3 knock down sample 1 (Cut & Run)
- GSM8958568 H4R3 knock down sample 2 (Cut & Run)
- GSM8958569 H4R3 knock down sample 3 (Cut & Run)
- GSM8958570 RNAPol2 knock down sample 1 (Cut & Run)
- GSM8958571 RNAPol2 knock down sample 2 (Cut & Run)
- GSM8958572 knock down IgG sample 1 (Cut & Run)
- GSM8958573 knock down IgG sample 2 (Cut & Run)
- GSM8958574 H4R3 sample in mEPC sample 1 (Cut & Run)
- GSM8958575 H4R3 sample in mEPC sample 2 (Cut & Run)
- GSM8958576 PRMT1 sample in mEPC sample 1 (Cut & Run)
- GSM8958577 PRMT1 sample in mEPC sample 2 (Cut & Run)
- GSM8958578 IgG mEPC control sample 1 (Cut & Run)
- GSM8958579 IgG mEPC control sample 2 (Cut & Run)
- GSE214631 Targeting tumor-intrinsic N7-methylguanosine tRNA modification inhibits MDSC recruitment and improves anti-PD-1 efficacy 14 samples shares modification, recruitment
- GSE286875 Improved spike-in normalization clarifies the relationship between active histone modifications and transcription 244 samples shares modification
- GSE32663 Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification 9 samples shares modification
- GSE285764 Single Alkyl Phosphonate Modification of the siRNA Backbone in the Seed Region Enhances Specificity and Therapeutic Profile 110 samples shares modification
- GSE240863 Single cell discovery of m6A RNA modifications in the hippocampus 43 samples shares modification
- GSE124718 Resetting histone modifications during human parental-to-zygotic transition 42 samples shares modification
- GSE286384 METTL3-dependent m6A RNA Modifications Orchestrate the HNF1B-associated Redox and the Metabolic Vulnerability in Cancer [RNA-seq] 40 samples shares modification
- GSE172146 Aberrant translation regulation by METTL1/WDR4-mediated tRNA N7-methylguanosine modification drives HNSCC progression 28 samples shares modification
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.