GEO series
PRMT1 recruitment and H4R3Me2a modification in control and PRMT1-depleted trophoblast progenitor
GSE295846
Homo sapiens; Mus musculus
Genome binding/occupancy profiling by high throughput sequencing
25 samples
2026/06/15
GPL24247GPL24676
Summary
To understand PRMT1 recruitment and associated changes in histone H4 arginine3 di-methylation at the chromatin region in trophoblast progenitors, we performed CUT&RUN experiments in CT27 human trophoblast stem cells (CT27 hTSCs) and in primary trophoblast stem and progenitor cells (TSPCs) in mouse embryonic day (E) 7.5 ectoplacental cone region (EPC). For CT27 hTSCs, experiments were done in both control and PRMT1-knockdown CT27 hTSC. We also tested RNA polymerase II recruitment in these cells.
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