Transcription factor NFYA directs male meiotic entry by facilitating accessible chromatin at the promoters of genes expressed during meiosis [CUT&RUN]
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 13 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 13 samples: 3 × CUT&Run (NFYA) of sorted leptotene/zygotene cells from adult testis, vs 3 × CUT&Run (NFYA) of sorted pachytene/diplotene cells from adult testis, vs 3 × CUT&Run (NFYA) of sorted Spermatogonia cells from adult testis,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Transcription factor NFYA directs male meiotic entry by regulating accessible chromatin at meiotic promoters in miceThe EMBO journal · 2026
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE295964_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1256871 and SRA study SRP582234. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 9 samples.
How we read this: 3 replicated groups read from 13 sample titles; they account for 9 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8962348 CUT&Run(H3K4me3) of sorted pachytene/diplotene cells from adult testis
- GSM8962349 CUT&Run (IgG) of sorted leptotene/zygotene cells from adult testis
- GSM8962350 CUT&Run (IgG) of sorted pachytene/diplotene cells from adult testis
- GSM8962351 CUT&Run (IgG) of sorted Spermatogonia cells from adult testis
- GSM8962352 CUT&Run (NFYA) of sorted leptotene/zygotene cells from adult testis,replicate 1 CUT&Run (NFYA) of sorte…
- GSM8962353 CUT&Run (NFYA) of sorted leptotene/zygotene cells from adult testis,replicate 2 CUT&Run (NFYA) of sorte…
- GSM8962354 CUT&Run (NFYA) of sorted leptotene/zygotene cells from adult testis,replicate 3 CUT&Run (NFYA) of sorte…
- GSM8962355 CUT&Run (NFYA) of sorted pachytene/diplotene cells from adult testis,replicate 1 CUT&Run (NFYA) of sorte…
- GSM8962356 CUT&Run (NFYA) of sorted pachytene/diplotene cells from adult testis,replicate 2 CUT&Run (NFYA) of sorte…
- GSM8962357 CUT&Run (NFYA) of sorted pachytene/diplotene cells from adult testis,replicate 3 CUT&Run (NFYA) of sorte…
- GSM8962358 CUT&Run (NFYA) of sorted Spermatogonia cells from adult testis, replicate 1 CUT&Run (NFYA) of sorte…
- GSM8962359 CUT&Run (NFYA) of sorted Spermatogonia cells from adult testis, replicate 2 CUT&Run (NFYA) of sorte…
- GSM8962360 CUT&Run (NFYA) of sorted Spermatogonia cells from adult testis, replicate 3 CUT&Run (NFYA) of sorte…
- GSE296438 Transcription factor NFYA directs male meiotic entry by facilitating accessible chromatin at the promoters of genes expressed during meiosis [scRNA-seq & scATAC-seq] 10 samples shares nfya, transcription, facilitating, accessible, chromatin, promoters
- GSE274875 A mutant ASXL1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia [Cut & Run] 38 samples shares cut, run, chromatin
- GSE282802 KMT2D controls cerebellar granule cell differentiation by temporally activating neuronal transcriptional factor genes [CUT&RUN] 10 samples shares cut, run, transcription
- GSE303384 Mechanism of maintenance and establishment of repression by the Mtg16 tumor suppressor [CUT&RUN, ChIP-Seq] 92 samples shares cut, run
- GSE306261 Astrocyte glucocorticoid receptor signaling restricts neuronal plasticity [CUT&RUN] 50 samples shares cut, run
- GSE292333 H2AK119ub1-MLL2 counteraction underlies heritable H3K27me3 formation in oocytes [CATCH-seq and CUT&RUN] 44 samples shares cut, run
- GSE298002 Stage-specific Epigenetic Priming Amplifies Gene Activation During Lineage Commitment [CUT&Run] 38 samples shares cut, run
- GSE293129 Enhancer rewiring orchestrates inflammation and loss of cell identity during muscle stem cell aging [CUT&RUN] 36 samples shares cut, run
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.