RNA-seq of RSV-Infected THP-1 Cells Treated with Recombinant CTSC
RNA-seq (gene expression) · human · 12 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Homo sapiens (human)
- Samples
- 12 samples: 3 × THP-1,PMA,PBS, vs 3 × THP-1,PMA,RSV, vs 3 × THP-1,PMA,rhCTSC,RSV, vs 3 × THP-1,PMA,rhCTSC,Sivaltat,RSV,Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- Cathepsin C orchestrates RSV-induced asthma exacerbation through the dual effect of monocyte-derived macrophagesCellular & molecular immunology · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE296019_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1259035 and SRA study SRP583155. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 12 samples.
How we read this: 4 replicated groups read from 12 sample titles; they account for 12 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8963532 THP-1,PMA,PBS,1 THP-1,PMA,PBS,
- GSM8963533 THP-1,PMA,PBS,2 THP-1,PMA,PBS,
- GSM8963534 THP-1,PMA,PBS,3 THP-1,PMA,PBS,
- GSM8963535 THP-1,PMA,RSV,1 THP-1,PMA,RSV,
- GSM8963536 THP-1,PMA,RSV,2 THP-1,PMA,RSV,
- GSM8963537 THP-1,PMA,RSV,3 THP-1,PMA,RSV,
- GSM8963538 THP-1,PMA,rhCTSC,RSV,1 THP-1,PMA,rhCTSC,RSV,
- GSM8963539 THP-1,PMA,rhCTSC,RSV,2 THP-1,PMA,rhCTSC,RSV,
- GSM8963540 THP-1,PMA,rhCTSC,RSV,3 THP-1,PMA,rhCTSC,RSV,
- GSM8963541 THP-1,PMA,rhCTSC,Sivaltat,RSV,1 THP-1,PMA,rhCTSC,Sivalt…
- GSM8963542 THP-1,PMA,rhCTSC,Sivaltat,RSV,2 THP-1,PMA,rhCTSC,Sivalt…
- GSM8963543 THP-1,PMA,rhCTSC,Sivaltat,RSV,3 THP-1,PMA,rhCTSC,Sivalt…
- GSE269126 RNA-seq analysis of the transcriptomic profiles of ATO+DAC-treated THP-1 cell lines expressing p53-R282W, vector control, or p53-R282W with IRF7 knockdown 11 samples shares thp-1, rna-seq, treated
- GSE318211 RNA-seq of human aortic smooth muscle cells treated with recombinant sST2 and angiotensin II 6 samples shares recombinant, rna-seq, treated
- GSE327840 RNA-seq profiling of LPS tolerance in monocytes, THP-1, fibroblasts, smooth muscle cells, and endothelial cells 58 samples shares thp-1, rna-seq
- GSE327277 Bulk RNA-seq analysis of Delta-like 4 (Dll4) knockdown in LPS- or TNF-α-stimulated THP-1 cells 20 samples shares thp-1, rna-seq
- GSE278916 RNA sequencing in untreated (UN), sodium arsenite (SA) and heat shock (HS) stressed HeLa,HUVEC and THP-1 cells 18 samples shares thp-1, treated
- GSE268256 Transcriptional profiling of DNA sensing signal activation of THP-1 cells using bulk RNA-seq and single cell RNA-seq 17 samples shares thp-1, rna-seq
- GSE176294 Revealing immune responses in the Mycobacterium avium subsp. paratuberculosis-infected THP-1 cells using single cell RNA-sequencing 16 samples shares thp-1, rna-seq
- GSE341769 RNA sequencing analysis of THP-1 cells treated with chlorquinaldol 12 samples shares thp-1, treated
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.