← BioTransfer GEO Dataset Finder
GEO series

ARP-1 wild-type and ARP-1 carfilzomib-resistant cells RNA-seq analysis

GSE296076 Homo sapiens Expression profiling by high throughput sequencing 4 samples Submitted 2026/07/01 Platform GPL16791
Summary
Proteasome inhibitors (PIs) such as carfilzomib (Cfz) are highly efficacious for patients with Multiple myeloma (MM). However, relapses and acquired resistance to PI treatment emerges in most patients. Here, we established Cfz-resistant MM cells. RNA-seq analysis revealed significant alterations in cholesterol- and lipid-related metabolic pathways in the resistant cells.
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE296076_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 4 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1257777 and SRA study SRP582574. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 4 more — browse all 4 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.