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Elucidating the impact of chemotherapy on skeletal progenitors [bulk ATAC-seq]

GSE296759 Mus musculus Genome binding/occupancy profiling by high throughput sequencing 6 samples Submitted 2026/06/15 Platform GPL34328
Summary
Mice receiving cyclic doxorubicin (DOX) treatment exhibited long-term skeletal defects. Lineage tracing experiments revealed loss of osteogenesis from bone marrow mesenchymal stem and progenitor cells. We performed molecular characterization on MSPCs to understand the mechanisms underying MSPC dysfunction folloiwng DOX treatment.
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Also filed as BioProject PRJNA1261012 and SRA study SRP584200. Searching any of these in the dataset finder brings you back here.

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