Preclinical and first-in-human of Purinostat Mesylate, a novel selective HDAC I/IIb inhibitor, in relapsed or refractory multiple myeloma and lymphoma [PDX]

Direct links to NCBI, no account and no request form: the whole study as GSE296833_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1261791 and SRA study SRP584711. Searching any of these in the dataset finder brings you back here.

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• GSE309595 Longitudinal Analysis of Multiple Myeloma: Therapeutic Response and Immune Microenvironment Dynamics in the Context of Tumor Heterogeneity [scRNA-seq] 270 samples
• GSE226176 Expression data of multiple myeloma patients at various stages of disease 23 samples
• GSE271107 Single-cell RNA sequencing of bone marrow aspirate samples from multiple myeloma and its precursor conditions 19 samples
• GSE284666 SenCat: Redefining human cell senescence through multiomic profiling of multiple senescent cell types 190 samples
• GSE330029 Temporal changes in metabolism guide oligodendrocyte precursor cell dynamics in aging and multiple sclerosis [BulkRNAseq] 108 samples
• GSE296117 A single-cell RNA-seq dataset of synovial fluid from rheumatoid arthritis treated with TNF-α/JAK inhibitor 18 samples
• GSE341139 A conserved HAND2-BMP5-SMAD1/5/9 axis drives hepatic stellate cell activation and extracellular matrix overproduction in multiple fibrotic etiologies 10 samples
• GSE314342 Genome-scale perturb-seq in primary human CD4+ T cells reveals genes regulating T cell programs and human immune traits. 577 samples

Search all human RNA-seq datasets in GEO →