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Differentiation of tumor-infiltrating GZMK+ effector memory T cells associates with response to neoadjuvant immunotherapy in head and neck cancer

GSE296954 Homo sapiens Expression profiling by high throughput sequencing 44 samples 2026/06/15 GPL21290GPL24676
Summary
We performed single-cell RNA/VDJ-sequencing of sorted T cells from pre- and post-treatment tumor biopsies of patients with HPV-unrelated head and neck squamous cell carcinoma treated with either bintrafusp alfa alone or in combination with Tri-Ad5 vaccine.
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