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Rifamycin O as a Novel CRBN Ligand for Targeted Degradation of IKZF1/3 Proteins in Hematopoietic Malignancies

GSE297439 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2026/05/01 Platform GPL24676
Summary
We found that Rifamycin O could effectively suppressed the hematologic tumors growth in vitro and in vivo. The antitumor effect of Rifamycin O is first identified so far.
Published in
Rifamycin O as a novel CRBN ligand for targeted degradation of IKZF1/3 proteins in hematopoietic malignancies
Liao L, Wang Q, Gao Z et al. · Acta pharmaceutica Sinica. B 2026 · PMID 41584346 · doi:10.1016/j.apsb.2025.10.033
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Also filed as BioProject PRJNA1263846 and SRA study SRP585995. Searching any of these in the dataset finder brings you back here.

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