STING activation induces cytotoxic and immune responses in meningiomas via inflammatory cell death pathways
ChIP-seq / ATAC-seq (genome binding and open chromatin) · human · 20 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Homo sapiens (human)
- Samples
- 20 samples: 20 samples, each with a distinct title — no replicated groupsGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
- Paper
- STING activation induces cytotoxic and immune responses in meningiomas via inflammatory cell death pathwaysNature communications · 2026
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE297764_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1266137 and SRA study SRP586539. Searching any of these in the dataset finder brings you back here.
Supports a case/control comparison: 12 samples read as cases, 2 as controls.
How we read this: Read from 20 sample titles: 20 distinct titles with little repetition. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM8995952 Meningioma Cells from Patient ITA-56, Control Treatment
- GSM8995953 Meningioma Cells from Patient ITA-56, 8803 Treatment
- GSM8995954 Meningioma Cells from Patient ITA-72, Control Treatment
- GSM8995955 Meningioma Cells from Patient ITA-72, 8803 Treatment
- GSM8995956 Meningioma Cells from Patient NU3971, Control Treatment
- GSM8995957 Meningioma Cells from Patient NU3971, 8803 Treatment
- GSM8995958 Meningioma Cells from Patient NU3981, Control Treatment
- GSM8995959 Meningioma Cells from Patient NU3981, 8803 Treatment
- GSM8999045 Frozen Meningioma Sample from Patient NU1795M, GEX
- GSM8999046 Frozen Meningioma Sample from Patient NU1795M, ATAC
- GSM8999047 Frozen Meningioma Sample from Patient NU0821, GEX
- GSM8999048 Frozen Meningioma Sample from Patient NU0821, ATAC
- GSM8999049 Frozen Meningioma Sample from Patient NU1142, GEX
- GSM8999050 Frozen Meningioma Sample from Patient NU1142, ATAC
- GSM8999051 Frozen Meningioma Sample from Patient NU1617, GEX
- GSM8999052 Frozen Meningioma Sample from Patient NU1617, ATAC
- GSM9562076 MGS1 orthotopic model pooled replicate 1 (Control)
- GSM9562077 MGS1 orthotopic model pooled replicate 2 (Control)
- GSM9562078 MGS1 orthotopic model pooled replicate 1 (8803)
- GSM9562079 MGS1 orthotopic model pooled replicate 2 (8803)
- GSE244947 NOTCH1 reverses immune suppression in small cell lung cancer through reactivation of STING 87 samples shares sting, activation
- GSE244945 NOTCH1 reverses immune suppression in small cell lung cancer through reactivation of STING [RNA-seq] 69 samples shares sting, activation
- GSE310025 Intrinsic RB activation induces tumoral and stromal anti-tumor responses that limit triple-negative breast cancer [RNA-Seq] 28 samples shares activation, induces
- GSE304030 oHSV-mediated JAG1 blockade induces glioma senescence-associated secretory phenotype to increase macrophage activation and sensitize to cetuximab-mediated senolysis 24 samples shares activation, induces
- GSE241338 Genome-wide interference of chromatin architecture and Mediator in transcriptional bursting and gene network regulation 250 samples shares sting
- GSE248942 Spatiotemporal control of SMARCA5 by a MAPK-RUNX1 axis distinguishes mutant KRAS-driven pancreatic malignancy from tissue regeneration (ATAC-Seq) 123 samples shares sting
- GSE290682 Nuclear class 3 PI3K co-activates fasting-specific chromatin remodeling 63 samples shares sting
- GSE218241 PIKfyve inhibition synergizes with Cisplatin to provoke antitumor immunogenicity in melanoma by alleviating lysosomal degradation of STING 18 samples shares sting
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.