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Transcriptomic analysis of chemotherapy-associated oropharyngeal candidiasis reveals a novel role of indigenous mucosal bacteria in pathogenesis

GSE297794 Mus musculus Expression profiling by high throughput sequencing 6 samples Submitted 2025/12/30 Platform GPL19057
Summary
This work reports a new mechanism of pathogenic synergy between C. albicans and E. faecalis, which may be responsible for increased epithelial barrier damage and mucosal invasion by C. albicans hyphae in cancer chemotherapy.
Published in
Enterococcus faecalis induces H₂O₂-mediated epithelial cell death and enhances Candida albicans virulence in oropharyngeal candidiasis
Vazquez-Munoz R, Ranjan A, Bertolini M et al. · mSphere 2026 · PMID 41474336 · doi:10.1128/msphere.00822-25
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Also filed as BioProject PRJNA1266194 and SRA study SRP586955. Searching any of these in the dataset finder brings you back here.

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