GEO series
scRNAseq and scTCRseq data from tumor-infiltrating lymphocytes
GSE298152
Mus musculus
Expression profiling by high throughput sequencing; Other
16 samples
2025/05/27
GPL24247
Summary
In cancer models, CD103+CD8 TRM cells are implicated in the response to anti-PD-1 immunotherapy, and a subset of CD4 TRM cells expressing the integrin CD49a is required for response to anti-CTLA-4 immunotherapy. We performed single-cell RNA sequencing on tumour-infiltrating T lymphocytes (TILs) isolated from colon carcinoma et unsupervised analyses reveal several TRM populations.
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Paper (PMID 40593647) ↗
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