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Chemical reprogramming of human blood cells into hCiPS cells [scRNA-seq]

GSE298212 Homo sapiens Expression profiling by high throughput sequencing 5 samples Submitted 2025/07/30 Platform GPL24676
Summary
Chemical reprogramming offers a fundamentally innovative approach for generating human pluripotent stem (hCiPS) cells using small molecules. Our recent studies showed that this approach was highly efficient in reprogramming human fibroblasts to hCiPS cells. In this study, we established a robust method that successfully generated hCiPS cells from both cord blood and adult peripheral blood cells. This method achieved efficient reprogramming with both fresh and cryopreserved blood cells.
Published in
Chemical reprogramming of human blood cells to pluripotent stem cells
Peng F, Wang Y, Cheng L et al. · Cell stem cell 2025 · PMID 40744016 · doi:10.1016/j.stem.2025.07.003
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Also filed as BioProject PRJNA1268522 and SRA study SRP588043. Searching any of these in the dataset finder brings you back here.

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