← BioTransfer GEO Dataset Finder
GEO series

Single-cell RNA sequencing of breast cancer patient-derived organoids

GSE298343 Homo sapiens Expression profiling by high throughput sequencing 6 samples Submitted 2025/05/29 Platform GPL24676
Summary
Patient-derived organoids have shown great promise as models of human tumors. However, a detailed single-cell description of the heterogeneity of these models is still lacking and limits their future clinical use. Here we performed a 10X single-cell RNA sequencing experiment to study the single-cell phenotype of breast cancer patient-derived organoids from 6 donors.
Published in
A stratification system for breast cancer based on basoluminal tumor cells and spatial tumor architecture
Meyer L, Jackson HW, Eling N et al. · Cancer cell 2025 · PMID 40680742 · doi:10.1016/j.ccell.2025.06.019
This dataset
Download

Direct links to NCBI, no account and no request form: the whole study as GSE298343_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 6 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1268996 and SRA study SRP588381. Searching any of these in the dataset finder brings you back here.

Samples in this study

The sample list for this study is not cached yet. Press Sort into groups and it will be fetched from NCBI.

+ 6 more — browse all 6 samples with per-sample file links →

Similar datasets

Search all human RNA-seq datasets in GEO →

Share this dataset

Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.