The CARM1 Epigenetic Enzyme Inhibits Cross-presenting Dendritic Cell Function in Cancer Immunity [RNA-seq]
RNA-seq (gene expression) · mouse · 26 samples
- What it is
- RNA-seq (gene expression)Gene activity measured by sequencing. The summary does not mention single-cell work, so this is most likely bulk: one average per sample, the usual starting point for comparing groups.
- Organism
- Mus musculus (mouse)
- Samples
- 26 samples: 6 × MSR scaffold from mice vaccinated with control vaccine, vs 4 × MSR scaffold from mice vaccinated with EZM2302 vaccine, vs 3 × control cDC1 vs 3 × Carm1-KO cDC1Groups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Read the full summary ↓
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE300014_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: For RNA-seq the counts are usually a table among the supplementary files (look for 'counts', 'expression', 'FPKM' or 'TPM' in the file name). The series matrix of a sequencing study is sometimes nearly empty.
Also filed as BioProject PRJNA1278705 and SRA study SRP592634. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 16 samples.
How we read this: 4 replicated groups read from 26 sample titles; they account for 16 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9052441 control cDC1 bio rep1 control cDC1
- GSM9052442 control cDC1 bio rep2 control cDC1
- GSM9052443 control cDC1 bio rep3 control cDC1
- GSM9052444 Carm1-KO cDC1 bio rep1 Carm1-KO cDC1
- GSM9052445 Carm1-KO cDC1 bio rep2 Carm1-KO cDC1
- GSM9052446 Carm1-KO cDC1 bio rep3 Carm1-KO cDC1
- GSM9052447 MSR scaffold from mice vaccinated with control vaccine, bio rep1 MSR scaffold from mice …
- GSM9052448 MSR scaffold from mice vaccinated with control vaccine, bio rep2 MSR scaffold from mice …
- GSM9052449 MSR scaffold from mice vaccinated with control vaccine, bio rep3 MSR scaffold from mice …
- GSM9052450 MSR scaffold from mice vaccinated with control vaccine, bio rep4 MSR scaffold from mice …
- GSM9052451 MSR scaffold from mice vaccinated with control vaccine, bio rep5 MSR scaffold from mice …
- GSM9052452 MSR scaffold from mice vaccinated with control vaccine, bio rep6 MSR scaffold from mice …
- GSM9052453 MSR scaffold from mice vaccinated with EZM2302 vaccine, bio rep1 MSR scaffold from mice …
- GSM9052454 MSR scaffold from mice vaccinated with EZM2302 vaccine, bio rep2 MSR scaffold from mice …
- GSM9052455 MSR scaffold from mice vaccinated with EZM2302 vaccine, bio rep3 MSR scaffold from mice …
- GSM9052456 MSR scaffold from mice vaccinated with EZM2302 vaccine, bio rep4 MSR scaffold from mice …
- GSM9052457 MSR scaffold from mice vaccinated with control vaccine, bio rep1s
- GSM9052458 MSR scaffold from mice vaccinated with control vaccine, bio rep2s
- GSM9052459 MSR scaffold from mice vaccinated with control vaccine, bio rep3s
- GSM9052460 MSR scaffold from mice vaccinated with control vaccine, bio rep4s
- GSM9052461 MSR scaffold from mice vaccinated with control vaccine, bio rep5s
- GSM9052462 MSR scaffold from mice vaccinated with control vaccine, bio rep6s
- GSM9052463 MSR scaffold from mice vaccinated with EZM2302 vaccine, bio rep1s
- GSM9052464 MSR scaffold from mice vaccinated with EZM2302 vaccine, bio rep2s
- GSM9052465 MSR scaffold from mice vaccinated with EZM2302 vaccine, bio rep3s
- GSM9052466 MSR scaffold from mice vaccinated with EZM2302 vaccine, bio rep4s
- GSE300019 The CARM1 Epigenetic Enzyme Inhibits Cross-presenting Dendritic Cell Function in Cancer Immunity [multiome] 8 samples shares carm1, cross-presenting, epigenetic, dendritic, inhibits, immunity, enzyme
- GSE245838 Anchored screening identifies transcription factor blueprints underlying dendritic cell diversity and subset-specific anti-tumor immunity [mouse scRNA-seq] 21 samples shares dendritic, immunity, rna-seq
- GSE327604 Epigenetic control of microglial mitochondrial immunity by KAT7 drives Alzheimer’s disease pathogenesis [RNA-Seq] 12 samples shares epigenetic, immunity, rna-seq
- GSE241770 ACSS2 mediates an epigenetic pathway to regulate maternal Beta-cell adaptation and progression of gestational diabetes (scRNA-Seq) 7899 samples shares epigenetic, rna-seq
- GSE243942 Spatio-temporal X-linked gene reactivation in the mouse germline reveals site-specific retention of epigenetic silencing [RNA-seq] 125 samples shares epigenetic, rna-seq
- GSE276155 RBBP5 is an epigenetic regulator of mammalian hepatic 12h oscillator [RNA-seq] 96 samples shares epigenetic, rna-seq
- GSE309564 IFNg shapes macrophage inflammatory responses by STAT1 isoform-specific epigenetic and transcriptional mechanisms [RNA-Seq] 72 samples shares epigenetic, rna-seq
- GSE270509 In vivo CRISPR screen reveals interplay of epigenetic regulators underlies kinetics of hepatobiliary reprogramming [RNA-Seq] 27 samples shares epigenetic, rna-seq
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.