Profiling Immune-Independent Response to Immune Checkpoint Inhibitors on Stem Cell-derived Cardiac Organoids [scRNAseq_Mouse]

Direct links to NCBI, no account and no request form: the whole study as GSE300367_RAW.tar, processed values as the series matrix, the supplementary file directory, and per-sample supplementary files for any of the 3 samples. Raw sequencing reads are also available from ENA.

Also filed as BioProject PRJNA1280158 and SRA study SRP593509. Searching any of these in the dataset finder brings you back here.

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• GSE300288 Single-cell and spatial transcriptomics analysis of tobacco-associated lung adenocarcinoma development, and in response to targeting inflammation alone or in combination with immune checkpoint blockade in precancerous phase [scRNA-seq] 31 samples
• GSE334497 TROP2/claudin program mediates immune exclusion to impede checkpoint blockade in breast cancer 10 samples
• GSE278990 Single-cell screens identify ADAM12 as a fibroblast checkpoint impeding anti-tumor immunity 73 samples
• GSE263383 Unbiased niche labeling maps immune-excluded niche in bone metastasis 33 samples
• GSE309993 Effector differentiation by stem-like intraepithelial γδ T cells is required for host defense against infection 25 samples
• GSE292862 Modelling mouse embryogenesis from chemically induced totipotent stem cells 22 samples
• GSE235046 Innate immune and metabolic signaling retain damaged mitochondria at cell membranes for mitoxyperilysis 15 samples
• GSE305453 Perturb-seq uncovers pathological obstacles to direct cardiac reprogramming in vivo 15 samples

Search all mouse RNA-seq datasets in GEO →