TET3 Promotes Tumor Immune Evasion Through Negative Regulation of Type I Interferon Signaling
ChIP-seq / ATAC-seq (genome binding and open chromatin) · mouse · 28 samples
- What it is
- ChIP-seq / ATAC-seq (genome binding and open chromatin)Where proteins bind the genome, or which regions are open and active.
- Organism
- Mus musculus (mouse)
- Samples
- 28 samples: 14 conditions, mostly in duplicateGroups are read from the sample names, not from the paper. Check the list below.
- Data you can get
- A processed table (series matrix) and supplementary files from NCBI; the raw sequencing reads from ENA. Which of these hold counts depends on the study, so check the file list.
Direct links to NCBI and ENA, no account and no request form. Pick by what you want to do: take the small processed table to look, the supplementary files to re-analyse, or the original raw data to start over.
Processed table
The series matrix: one table of values per sample as the submitters processed it. The smallest download, and it opens in Excel or R. Start here to see what the data look like.
Supplementary files
The count tables and other files the authors uploaded. Take only the samples you need, or the whole study as GSE300464_RAW.tar (it can run to tens of gigabytes).
Raw sequencing reads
The original FASTQ files, straight from the sequencer, held at ENA. Large, and you align them yourself, so only choose this if you need to re-process the study from scratch.
What the files usually look like: Look for peak files (.bed, .narrowPeak) and signal tracks (.bigWig) among the supplementary files; the raw reads are on ENA.
Also filed as BioProject PRJNA1280995 and SRA study SRP594078. Searching any of these in the dataset finder brings you back here.
Supports a between-group comparison across 28 samples.
How we read this: 14 replicated groups read from 28 sample titles; they account for 28 of them. These groups are guessed from the sample names, not taken from the paper, so check them against the sample list below before relying on them.
- GSM9060863 MCF7_WT_mRNAseq_rep1 MCF7_WT_mRNAseq
- GSM9060864 MCF7_WT_mRNAseq_rep2 MCF7_WT_mRNAseq
- GSM9060865 MCF7_TET3KO_mRNAseq_rep1 MCF7_TET3KO_mRNAseq
- GSM9060866 MCF7_TET3KO_mRNAseq_rep2 MCF7_TET3KO_mRNAseq
- GSM9060867 MCF7_shscramble_mRNAseq_rep1 MCF7_shscramble_mRNAseq
- GSM9060868 MCF7_shscramble_mRNAseq_rep2 MCF7_shscramble_mRNAseq
- GSM9060869 MCF7_shTET3-1_mRNAseq_rep1 MCF7_shTET3-1_mRNAseq
- GSM9060870 MCF7_shTET3-1_mRNAseq_rep2 MCF7_shTET3-1_mRNAseq
- GSM9060871 MCF7_shTET3-2_mRNAseq_rep1 MCF7_shTET3-2_mRNAseq
- GSM9060872 MCF7_shTET3-2_mRNAseq_rep2 MCF7_shTET3-2_mRNAseq
- GSM9060873 B16F10_WT_mRNAseq_rep1 B16F10_WT_mRNAseq
- GSM9060874 B16F10_WT_mRNAseq_rep2 B16F10_WT_mRNAseq
- GSM9060875 B16F10_Tet3KO_mRNAseq_rep1 B16F10_Tet3KO_mRNAseq
- GSM9060877 B16F10_Tet3KO_mRNAseq_rep2 B16F10_Tet3KO_mRNAseq
- GSM9060878 B16F10_siNC_RiboZero_rep1 B16F10_siNC_RiboZero
- GSM9060880 B16F10_siNC_RiboZero_rep2 B16F10_siNC_RiboZero
- GSM9060882 B16F10_siTet3-1_RiboZero_rep1 B16F10_siTet3-1_RiboZero
- GSM9060884 B16F10_siTet3-1_RiboZero_rep2 B16F10_siTet3-1_RiboZero
- GSM9060886 B16F10_siTet3-2_RiboZero_rep1 B16F10_siTet3-2_RiboZero
- GSM9060889 B16F10_siTet3-2_RiboZero_rep2 B16F10_siTet3-2_RiboZero
- GSM9060902 MCF7_WT_input_rep1 MCF7_WT_input
- GSM9060903 MCF7_WT_TET3ChIP_rep1 MCF7_WT_TET3ChIP
- GSM9060904 MCF7_TET3KO_input_rep1 MCF7_TET3KO_input
- GSM9060905 MCF7_TET3KO_TET3ChIP_rep1 MCF7_TET3KO_TET3ChIP
- GSM9060906 MCF7_WT_input_rep2 MCF7_WT_input
- GSM9060907 MCF7_WT_TET3ChIP_rep2 MCF7_WT_TET3ChIP
- GSM9060908 MCF7_TET3KO_input_rep2 MCF7_TET3KO_input
- GSM9060909 MCF7_TET3KO_TET3ChIP_rep2 MCF7_TET3KO_TET3ChIP
- GSE300460 TET3 Promotes Tumor Immune Evasion Through Negative Regulation of Type I Interferon Signaling [RNA-Seq] 20 samples shares tet3, interferon, promotes, negative, evasion, type
- GSE247936 YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies 46 samples shares promotes, evasion
- GSE269054 Spatially clustered type I interferon responses at injury borderzones 37 samples shares interferon, type
- GSE99311 Enhancer reprogramming promotes pancreatic cancer progression and metastasis 136 samples shares promotes
- GSE63782 Transcriptional plasticity promotes primary and acquired resistance to BET bromodomain inhibition 103 samples shares promotes
- GSE282171 Depression and Anxiety-Induced Metabolic Reprogramming Promotes Hepatocellular Carcinoma Progression through CBX5 Lactylation: Involvement of Taurocholate and PHGDH-Mediated Ferroptosis 28 samples shares promotes
- GSE312096 Inhibition of PAK2 in endothelial cells suppresses tumor angiogenesis and promotes immune sensitization through CXCL10 24 samples shares promotes
- GSE302075 3D-printed nHA/PA66 porous scaffold: Regulating immune balance and vascularization synergistically promotes bone regeneration 24 samples shares promotes
Metadata from NCBI GEO, cached and refreshed periodically — the NCBI page above is authoritative. Downloads link straight to NCBI/ENA; nothing is proxied through BioTransfer.